In 2000, Shepherd's bestselling autobiography was published, titled Cybill Disobedience: How I Survived Beauty Pageants, Elvis, Sex, Bruce Willis, Lies, Marriage, Motherhood, Hollywood, and the Irrepressible Urge to Say What I Think, written in collaboration with Aimee Lee Ball. That same year, Shepherd hosted a short-lived syndicated talk show version of the book Men Are from Mars, Women Are from Venus, but left the show in early 2001 and was replaced by Cristina Ferrare, Bo Griffin, Samantha Phillips, Drew Pinsky, and Rondell Sheridan. In 2003, she guest-starred on 8 Simple Rules as the sister of Cate Hennessy (portrayed by Katey Sagal). She has played Martha Stewart in two television films: Martha, Inc.: The Story of Martha Stewart (2003) and Martha: Behind Bars (2005).
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